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Investigated for effects on gene-expression patterns related to stress responses, antioxidant defenses, and apoptosis regulation

Previous studies have found that BPC-157 did not exert a direct effect in terms of accelerating the cell proliferation of cultured tendon fibroblasts,42 but our results suggested that BPC-157 modulates the cell viability and affects HUVEC cell cycle exit in G0/G1 phase

A 28-day administration of BPC 157 (4, 1, or 0.2 mg/kg/day, i.m.) in rats and (2, 0.5, or 0.1 mg/kg/day) in beagle dogs also resulted in no apparent changes as compared to saline-treated animals