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1 Introduction The glutathione peroxidase family (GPX) is a family of antioxidant enzymes that are an essential class of selenoenzymes in mammals (Zhao et al., 2019)

dioscoridis aerial portions are primarily composed of phenolics and terpenoids and contain 35% volatile oil

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After HT22 cytotoxicity evaluation compound 36 was found to have low cytotoxicity (CC 50 = 18.8 M) and its inhibitory activity was 16 times higher than that of OLZ (EC 50 = 0.074 M)