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M., Michieli P

Exercise intervention mitigates pathological liver changes in NAFLD zebrafish by activating SIRT1/AMPK/NRF2 signaling

Yes IGF-1 LR3 has significant insulin-like effects due to structural homology with insulin, causing direct activation of insulin receptors in addition to IGF-1 receptors

[DOI] [PubMed] [Google Scholar] 18.Mudd SH, Levy JL

HMOX1 Upregulation Promotes Ferroptosis in Diabetic Atherosclerosis
