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Visceral fat reduction decreases chronic low-grade inflammation (inflammaging), a key driver of age-related pathology ( 3.2 Growth hormone axis restoration Growth hormone (GH) secretion declines approximately 14% per decade after age 30, resulting in decreased lean body mass, increased adiposity (particularly visceral fat), reduced bone density, decreased skin thickness, and impaired recovery from illness or injury, a phenomenon termed somatopause ( CJC-1295, a long-acting GHRH analog incorporating a Drug Affinity Complex (DAC) for albumin binding, addresses somatopause by restoring more youthful GH secretion patterns ( Ipamorelin complements CJC-1295 by stimulating GH release through ghrelin receptor activation rather than GHRH pathways (Malavige et al., 2021)

[PubMed] [Google Scholar] 80.Grau M., Montero J.L., Balasch J

Similar content being viewed by others Introduction The liver is a vital organ that governs over hundreds of physiological processes, including nutrient metabolism 1 , detoxification 2 , bile secretion 3 , and protein synthesis 1 , serving as the bodys primary metabolic hub 4,5

Burns 31 (3), 310315