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Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase

This work was supported by the University of Manchester FBMH Sustainability Fund and by the Biotechnology and Biological Sciences Research Council (BBSRC) Doctoral Training Partnership (BBSRC grants BB/K019783/1 and BB/M017702/1)

This lack of antioxidant defence might be somehow compensated by increased, at the same time point, the GCS activity and GSH level (Ardite et al

S2 Kinetics of formation (t= 0, 0.5, 2, 6, 24 and 48h) of APAP metabolites in HRG cells and Hepatocytes after exposure to APAP and APAP-Cys, including a zoom of metabolites showing low intensity signals

napus (Ligaba et al., 2006), A