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Description
Many studies have found a high prevalence of elevated homocysteine among vegans who dont supplement with B12

Homocysteine thiolactone is reactive towards lysine residues in a process termed N-homocysteinylation

[13] There have also been rare reports of high-dose vitamin B (as in injectable form) precipitating skin outbreaks such as acne or rosacea in susceptible persons

K.Von ZastrowM.et al

On the basis of this idea, it has been predicted and validated that lower NAD + levels are a shared characteristic of ageing-related disease
