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PCD affects 15 people in 10,000 and most usually presents between the ages of 1 and 7 (Magoulas and El-Hattab, 2012)

In sex-specific analysis, as for l-carnitine, genetically predicted acetyl-carnitine was also related to higher risk of CAD in men (OR 1.09, 95% CI 1.02 to 1.16) but not in women (OR 1.00, 95% CI 0.92 to 1.09) (Additional file 2: Fig

Shrimal, S., Trueman, S

We also examined the time course of the anti-catabolic effects of L-carnitine by checking the MAFbx and MuRF1 expression levels after exposure to different concentrations of TNF- and L-carnitine

This amino acid plays an important role in cellular energy metabolism by aiding the transport of long-chain fatty acids to the cells, where they can be metabolised to produce energy