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There are different subtypes of opioid receptors and pharmacologists are continually trying to exploit the differences in these opioid receptors in order to activate pain ameliorating properties without also triggering untoward side effects, such as respiratory depression and reduction of gastrointestinal peristalsis (which can lead to bowel obstruction)

No findings suggest clinical relevance, therapeutic intent, or suitability for human or veterinary use

As pointed out by one of the coordinators, The planning is a bit floating

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Folic acid is not a substitute for Vitamin B12, even though they are both B vitamins