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Pachymic acid (PA), a lanolin-type triterpenoid, demonstrates ferroptosis-inhibitory properties by reducing MDA, ROS, and Fe 2 levels while upregulating GSH, SLC7A11, and GPX4, thereby alleviating MIRI [92]

But most formulas use tiny amounts that barely make a difference

Kamei J, Ohsawa M, Miyata S, Tanaka S (2008) Preventive effect of L-carnosine on changes in the thermal nociceptive threshold in streptozotocin-induced diabetic mice

MAIT cells, guardians of skin and mucosa

Similarly, alcohol and over-the-counter pain relievers like acetaminophen are heavily metabolized by the liver and rapidly deplete the body's natural glutathione stores