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In this study, the researchers observed a significant correlation between the number of mast cells and the levels of fatty infiltration and fibrosis in minor SG of 19 patients with pSS and 10 healthy individuals (125)
Plissonneau C, Sivignon A, Chassaing B, Capel F, Martin V, Etienne M

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This also indicates a role of APLN/APLNR signaling in the regulation of immunological processes, which needs to be further investigated

It has been demonstrated that ROS primarily stem from the electron transport chain (ETC) complex within mitochondria