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A 2015 study by Huang and colleagues in Drug Design, Development and Therapy used a rat alkali-burn model (n=10 per group) and HUVECs treated with BPC-157 at 200800 ng/mL, reporting accelerated wound closure with enhanced granulation tissue, reepithelialization, and dermal remodeling by day 18, alongside increased endothelial migration and vascular tube formation in vitro via ERK1/2 phosphorylation though the abstract does not report numeric % wound closure or p-values

Interestingly, the oral administration of Chitosan@DOTAGA maintains normal WBC, MCHC, PLT, and HGB levels which present no statistical differences from the control mice evidencing a remarkable preventative effect of this treatment against the heavy metals

10.1155/2015/610813 [DOI] [PMC free article] [PubMed] [Google Scholar] Fraternale A., Zara C., De Angelis M., Nencioni L., Palamara A

Psychiatry 89 , A44A45 (2018)

Parent surveys about pediatric vaccine delivery found intranasal formulations significantly more tolerable and favorable compared to intramuscular injections