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Nucleic Acids Res 46:W443W450

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Established roles of NQO1 include its ability to prevent certain quinones from one electron redox cycling but its role in quinone detoxification is dependent on the redox stability of the hydroquinone generated by two-electron reduction

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In the myocardial ischemia/reperfusion model in vivo, EGCG preconditioning significantly decreased the levels of creatine kinase MB isoform and lactate dehydrogenase, increased the ATP levels, suppressed apoptosis, and partially preserved heart function [212]

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