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Some studies have reported FGF21s direct action on adipose tissue (Samms et al, 2016), whereas other studies propose that FGF21 acts through the central nervous system (CNS) to assert metabolic benefit (Bar-Ziv et al, 2020
The restraint stress involved confining rats in a commercially available flat-bottomed plexiglass rodent restrainers (Harvard Instruments)
[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Braun JEA, Severson DL
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