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doi: 10.1111/j.1582-4934.2008.00463.x

Epidemiological data indicate that GBM accounts for over 50% of malignant CNS tumors in adults [4]
It is studied in preclinical models for its effects on angiogenesis, fibroblast activity, collagen organization, and tissue protection

GPx1, 2 and 3 act as homotetramers, whereas GPx4 is functional as a monomer [2]