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Description
Targeted covalent inhibitor An inhibitor bearing a bond-forming functional group of low reactivity that, following binding to the target protein, is positioned to react rapidly with a specific non-catalytic residue at the target site

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Conversely, with the degradation of GPX4 using cyclophosphamide, AIF-dependent parthanatos was triggered to suppress tumor growth [145]

DOI: 10.3390/cells11030409 16
