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The results of these studies are mixed, and due to study design, it is difficult to draw comparisons or firm conclusions (see Table 5 in the supplementary data for a summary of the evidence)
Glutaredoxin 3 promotes migration and invasion via the Notch signalling pathway in oral squamous cell carcinoma
The reaction mechanism is as follows: GSSG + NADPH + H 2 GSH + NADP (catalyzed by GR) It's worth emphasizing that the GSH/GSSG ratio is a crucial indicator of cellular redox status
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Klein EA, et al
