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A., & Alam, M

The metagenomic data are deposited in GSA-Human under the accession number HRA009721 (BioProject accession: PRJCA032811), available at The proteomic data are deposited in the PRIDE database under the ProteomeXchange accession number PXD059894, with the project webpage available at and the FTP download at Ethics statement The studies involving humans were approved by Ethical Committee for Research with Medications (CEIM) at the Quirnsalud-Catalunya Hospital Group (protocol code IDI-20210749, approval record No

Variants of the low oxygen sensors EGLN1 and HIF-1AN associated with acute mountain sickness

In addition, the lysosomal dysfunction interfered with the autophagy flux and mTOR regulation of ATP synthesis, thus impairing energy metabolism and mitochondrial function [122]

When BMNs were treated with either BAPTA-AM or EGTA-AM simultaneously with PMA stimulation, BAPTA-AM showed superior inhibition of NET formation, highlighting that the Ca 2+ signal elicited in close proximity to XKR8 activation is essential for driving NET progression (Extended Data Fig