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TABLE 1 Overview of PDE isoforms, substrate specificity, brain expression, and biological effects

Caspase-1 promotes the maturation of IL-1 and IL-18, while also cleaving GSDMD into GSDMD-C and GSDMD-N (31)

Comparative effects of H+ and Ca2+ on large-conductance Ca2+- and voltage-gated Slo1 K+ channels

NOX4 does not require p47phox, p67phox and Rac1 subunits for activation [6]

doi: 10.1371/journal.pone.0085885 148 ZhangY.TalalayP.ChoC
