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Bernard R, Kerman IA, Thompson RC, Jones EG, Bunney WE, Barchas JD

Tesofensine is generally contraindicated for patients with uncontrolled hypertension, a history of arrhythmias, or severe anxiety disorders

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Therapeutic Prospective and Limitations Limiting side effects is of particular importance regarding angiotensin-based antihypertensive drugs given the documented problems of dry mouth, nausea and dizziness, muscle soreness, and diuresis that may occur with ACE inhibitors and ARBs