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Unsaturated VPA metabolites (4-en-VPA and 2, 4-dien-VPA) are potent inducers of microvesicular steatosis in rats, whereas VPA itself failed to induce discernible liver lesions at near lethal doses [60]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Aureli T, Di Cocco ME, Puccetti C, Ricciolini R, Scalibastri M, Miccheli A, Manetti C, Conti F

118 Di Lorenzo, C

International agency for research on cancer monograph working group
