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TDM has shown to be useful during treatment with thiopurines because of the small therapeutic range of 6-TGN concentrations balancing between therapeutic concentrations and toxicity [84]

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En alternative, il est galement possible de se supplmenter en acides amins prcurseurs du glutathion, tels que la N-actyl-cystine (NAC)

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Decreased plasma H 2 O 2 levels are associated with the pathogenesis leading to COVID-19 worsening and mortality

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