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In a mouse model of OCD involving marble burying behaviour, NAC dose-dependently decreased burying behaviour independent of locomotor activity.66) Pilot studies and case reports of NAC in the treatment OCD and OCRD have been published.39,67,68) Despite one generalised nutraceutical69) and one complementary medicine review70) for OCD and OCRD to date, there has been no specialised review collating the current clinical evidence specifically for NAC in OCD or OCRD
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Many therapeutic approaches that target GM have shown great promise in managing and treating PD
