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The beneficial effects of plants are attributed to the presence of secondary metabolites such as polyphenols, tannins, terpenoids, alkaloids, flavonoids [11]

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Rottapharm and Madaus invented coprecipitation processing in 1995, which significantly improved the production of silymarin

notably, it is essential for the translocation of Nuclear Factor of Activated T cells (NFAT) into the nucleus ( Figure 1 ) (78)

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