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As a result, folate deficiency can lead to many neuropsychiatric manifestations, such as depression, alterations in neurotransmitter function, DNA damage, as well as being associated with the development of autism spectrum disorders in children, neural tube irregularity and brain development defects (, , , , , , , )

Furthermore, SAM may affect the stability of the linkage to FAD, an essential cofactor of MTHFR

AICD is a specialized form of programmed cell death that occurs in chronically stimulated T cells following prolonged antigen exposure, serving as a critical mechanism to maintain immune homeostasis and peripheral tolerance (Zhang et al., 2000

The confidentiality of participants was preserved through the use of unique codes assigned to each sample and study data

Please note that this treatment is not recommended for pregnant or breastfeeding women