intracellular glutathione levels and cancer responsive nanomedicine leverages tumor redox imbalance for targeted theranostics | Discover Oncology Human cancer-associated fibroblasts enhance glutathione
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This is achieved in Complex IV (cytochrome oxidase) using a combination of hemes and copper centers [binuclear copper-A (Cu A ), cytochrome a, cytochrome a 3 , and copper-B] (Fig

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Gebhard D, Mittelman A, Lee BF, Andreeff M , Koziner B

The main pathological features of PD are the absence of dopaminergic neurons in the dense substantia nigra and accumulation of toxic Lewy bodies in the cytoplasm of neurons (13)

Design of a multi-sensor platform for integrating extracellular acidification rate with multi-metabolite flux measurement for small biological samples
