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Finally, a critical perspective will be provided on the main limitations and issues surrounding the use of polyphenols in general and in the context of IBDs in particular, based on the most updated scientific evidence

Animal studies show that after acute exhaustive exercise, M1 macrophages in the liver are activated (156), and macrophages migrate to muscle, liver, and kidney, promoting the release of pro-inflammatory cytokines and exacerbating tissue damage (157159)

2021;12(1):2048.[DOI] 204

Sarkar A, Lehto SM, Harty S, Dinan TG, Cryan JF, Burnet PWJ