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Description
The primary physiological role of L-Carnitine involves facilitating the transport of long-chain fatty acids across the inner mitochondrial membrane via the carnitine palmitoyltransferase (CPT) enzyme system

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The class I PI3K are the only PI3K enzymes that can generate PtdIns-3,4,5-P 3

BVR-A is a direct target of the IR kinase activity, and as part of a regulatory loop BVR-A phosphorylates IRS1 on inhibitory Ser residues to prevent IRS1 aberrant activation in response to IR
