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Research published in Biochemical Pharmacology demonstrates that systemic administration of 5-Amino-1MQ to diet-induced obese mice produced approximately 5.1% body weight loss and 35% reduction in white adipose tissue mass over 11 days of treatment, without affecting total food intake

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Not only does the resulting barrier disruption promote diarrhoea because of increased water concentration in the intestinal lumen, but there is also a greater opportunity for the development of secondary infections due to deeper tissue penetration by other pathogens and toxins (Guttman and Finlay 2009)

Takeaway: His main comment was that he wished he had not waited so long