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Additionally, metformins role in reducing the risk of cardiovascular events could be beneficial for patients experiencing vascular complications as part of their Long COVID presentation [26,27]

Further randomized controlled trials are necessary to establish definitive efficacy [162, 163]

Commun Biol 5 , 326 (2022)

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Although it is well-accepted that tight junctions are crucial for the maintenance of barrier integrity, the exact function of the individual tight junction proteins remain elusive