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Cancer treatments significantly elevate OS through multiple mechanisms: chemotherapeutic agents, particularly alkylating agents and platinum compounds, generate excessive ROS directly damaging sperm DNA and membranes (87, 88), while radiation therapy induces both acute and chronic OS states in testicular tissue, leading to prolonged spermatogenic dysfunction (95)

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Carnitine deficiencies are also found in patients undergoing hemodialysis or those affected by any one of various organic acidemias/acidurias (e.g

Ela ou seus metablitos, incluindo fosfolipdios, betaina e acetilcolina, asseguram a integridade estrutural e funes sinalizadoras das membranas celulares 2