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This hypothesis was directly tested in a double-blind, randomized controlled trial (RCT) by Walsh et al

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1

While each of these domains has been extensively discussed individually, it is their convergence that underlies the shared pathophysiological mechanisms observed in clinical and molecular studies

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Several studies suggest that antioxidant dysfunction and an overactive immune system are involved in the development of psoriasis [4]
