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Macrophages also contribute directly by releasing matrix vesicles that nucleate calcium phosphate deposits in vessel walls

TB Preventive Treatment, 2025)

For stroke, a trial of ebselen treatment and stroke showed some promising results of ebselen in improving outcomes [110], however this study has not been replicated and there is no clear association of stroke risk or outcomes with GPx1 polymorphisms [111, 112]

Tumour Biol (1988) 9(5):2418

However, if, for any reason, this physiological rate of ROS generation should increase, or the spermatozoa should become exposed to exogenous ROS generated by, for example, infiltrating leukocytes, then a state of oxidative stress can be readily induced