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This IGF-1 independence is the single most important experimental advantage of the AOD 9604 10mg research compound for researchers designing metabolic studies: the absence of IGF-1 elevation means that downstream anabolic, mitogenic, or glucose-modulating confounds associated with full-length hGH are not present in AOD-9604 experimental models

Materials and methods Animals Adult (810weekold), male C57BL/6 mice (Jackson Laboratories, Bar Harbor, ME) weighing between 20 and 25 g were used

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Assessment of mGluR5 KO mice under conditions of low stress using a rodent touchscreen apparatus reveals impaired behavioural flexibility driven by perseverative responses