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10.1078/0176-1617-00926 67 LascanoH

Glutathione S-Transferase P1 and Lung Function in Patients with Alpha1-Antitrypsin Deficiency and COPD. Chest, vol
glutamate further participates in the TCA cycle (via GLUD-mediated conversion to -KG) or acts as a signaling molecule to activate calcium-dependent PLC-/PKC pathway (through NR2B) and promote CCL2 expression, thereby recruiting tumor-associated macrophages

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The significance of MTHFR mutations can vary widely among individuals
