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Lee CA, Lillibridge JH, Nelson SD, Slattery JT: Effects of caffeine and theophylline on acetaminophen pharmacokinetics: P450 inhibition and activation

However, the intravenous route should only be used under medical supervision, as inappropriate administration can cause rare but serious complications

10.1186/s12951-024-02916-4 26 ChenL.YangN.ChenK.HuangY.LiuX.YuG.et al (2025)

Methods The drugs were tested as Pf GR potential inhibitors via molecular docking on AutoDock 4, which was performed based on the preoptimized structures in HF/3-21G-PCM level of theory on ORCA 5

Mechanistically, plumbagin interferes with the YTHDF1-mediated m 6 A methylation pathway that regulates SLC7A5 translation (84)