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Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease Neurology 1998

[DOI] [PubMed] [Google Scholar] 31.Rossini M., Di Munno O., Valentini G., Bianchi G., Biasi G., Cacace E., Malesci D., La Montagna G., Viapiana O., Adami S

The heart and gastrointestinal tract are connected through a dynamic network of microbial, immune, and metabolic signals, known as the gutheart axis

Medications that can cause acute angle-closure, such as topiramate or strong anticholinergic drugs, may trigger symptoms within hours to days of starting treatment, though topiramate-related angle-closure most commonly occurs within the first two weeks
One of the enzymes in this pathway, -butyrobetaine hydroxylase, is absent from cardiac and skeletal muscle but highly expressed in human liver, testes, and kidney [4]
