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Although randomized studies have not shown an overall effect on the frequency of exacerbations, a post-hoc analysis of a clinical trial reported a decrease in their severity (87) Overall, these results demonstrate that A1PI augmentation therapy offers significant benefits in slowing the progression of emphysema and improving clinical outcomes for patients with AATD, underscoring the importance of timely and continuous treatment
Mechanisms of action of Ginkgo biloba compounds include free radical scavenging for antioxidant activity, antagonistic effects on platelet-activating factor, vasodilation, and an overall reduction in blood viscosity [183,187]
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Carcinogenesis 6 , 165172 (1985)
NO might have either oncogenic or antitumor effect [44] depending on the its concentration, duration of cell exposure, and cell adaptation
