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Additionally, the vast majority of psychiatric drugs display a high potential for physiological dependence [370, 371] which would make testing and use in pediatric populations challenging and potentially risky, if not redundant

The presence of an excess of VLCFA, mainly hexacosanoic acid (C26:0), a substrate of peroxisomal beta-oxidation, in ALD fibroblasts has been found to trigger oxidative stress and decrease the mitochondrial membrane potential [112]

Coordination Chemistry of Nitrosyls and Its Biochemical Implications

Endocrinology 132, 27292731

McIlwain H, Silverfield JC, Cheatum DE, Poiley J, Taborn J, Ignaczak T, et al