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L.DaoE.TamR.EngJ
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Administrated resveratrol positively affects the synthesis of sirtuins, SIRT1 (a family of proteins NAD + -dependent histone deacetylases playing an important role in the regulation of metabolic pathways, see below) activating then superoxide dismutase 2 (Mn-SOD) expression in cardiomyocytes and improved cardiac functions (Tanno et al
Oncogene (2017) 36:352840
CK-MT crystallography identified dual anchoring, an N-terminal mitochondrial targeting sequence (31 residues) and a C-terminal cardiolipin-binding motif, ensuring stable integration at mitochondrial contact sites [25]
