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This was achieved by increasing the M2/M1 macrophage ratio and the expression of IL4, reducing the secretion of IL6 and IL1, as well as clearing excessive ROS both in vitro and in vivo

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The mutant exhibited decreased virulence of and a reduced host immune response, as the fungal cells were more susceptible to H 2 O 2

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Ledoux J, Taylor MS, Bonev AD, et al