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PROTEOMIC IDENTIFICATION OF REDOX PTMs While the identification of reactive cysteines is crucial for understanding protein function and regulation, there is no universal signature allowing their identification

10.1099/mic.0.000909 [DOI] [PubMed] [Google Scholar] Investigation of protein quality (1968)

10.1016/j.yexcr.2024.114053 142 YuanS.ChuY.LiuF.XiaoY

Therefore, melatonin can inhibit the growth of breast cancer cells in the MCF-7 and MDA-MB-231 cell lines by inducing cell death by increasing the expression of the apoptotic markers TUNEL and Bax and the autophagy Beclin-1, LC3, and p62 [37]

Furthermore, excessive ROS that are generated by some chemo-reagents, radiation, or photodynamic therapy (PDT) would induce immunogenic cell death (ICD) of tumor cells, and the released immunogenic molecules such as high-mobility group box 1 protein (HMGB1), ATP, and damage-associated molecular patterns (DAMPs) can activate the immunity of DCs and T cells [24, 25]