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Engineers, basic scientists, and clinicians must work together to bridge the gap between bench and bedside
The trans-3-hexenoyl group on the N-terminal tyrosine acts as a protective cap against dipeptidyl peptidase-IV (DPP-IV), the enzyme that cleaves native GHRH between residues 2 and 3 and generates the short plasma half-life that limits unmodified GHRH activity
NSP5 - main SARS-CoV-2 protease
