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Pete G, Hu Y, Walsh M, Sowers J, Dunbar JC: Insulin-like growth factor-I decreases mean blood pressure and selectively increases regional blood flow in normal rats

Normally, this GSSG is recycled by reductases to maintain sufficient intracellular levels of reduced GSH

The use of iNap1 monitored NADPH fluorescence as a readout has advantage because it converges multiple signaling pathways including PPP, folate metabolism and ME1 pathway 11,13

Both cytokines induce muscle atrophy via either direct catabolic effects or through indirect mechanisms such as inhibition of IGF-I production and its signaling pathway[29]

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