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While they share some similarities in symptoms, they differ in their causes and how they are treated

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In experimental models, this relationship places TB-500 within a broader signaling environment that integrates structural cell biology with intracellular signaling cascades

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Structure and mode of action A molecule of HSP70 consists of an N-terminal nucleotide-binding domain (NBD), a substrate-binding domain (SBD), a linker region connecting the two, and variable C-terminal motifs such as EEVD (Figure 1)