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Kratom alkaloids are renowned for their ability to bind a wide range of peripheral and central nervous system receptors [43], including serotonin receptors [44, 45]

doi: 10.1016/j.jenvman.2019.109557 23

In addition, certain medical conditions and medications can cause vitamin B12 deficiency (30)

doi: 10.1016/j.chom.2023.01.004 225 ChenJChiaNKalariKRYaoJZNovotnaMPaz SoldanMMet al

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