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The limited number of qualifying curcumin studies reveals essential trends in current research directions

The early human pharmacology data remains in the published record and continues to inform preclinical-to-translational research frameworks
Additionally, DL models (such as three-dimensional convolutional neural network (3D-CNN)) can analyze trajectory data to predict dynamic changes at binding sites, effectively lowering computational costs and improving simulation accuracy (Peivaste et al., 2024

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