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Alcohol interferes with normal nutrient balance and blood chemistry, which contributes to common hangover effects such as weakness, headaches, and cognitive impairment

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JNCI Monogr

Of note, cytokines have a very short half-life in blood, i.e., several minutes and thus may not be useful for diagnostic purposes, in contrast to APPs with a half-life of several hours [114], though they would be expected to appear following the cytokines

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