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Moreover, the BPC 157-activated bypassing key might act through modulatory effects on the prostaglandins system (i.e., counteracting non-steroidal anti-inflammatory drugs (NSAIDs) toxicity (for review, see i.e., [35]) and leaky gut syndrome (for review, see, i.e., [4]), acting also as a free radical scavenger [4,36,37,38]) and through modulatory effects on the nitric oxide (NO) system (i.e., interaction with NO agents in various models and species) [39], and in particular through special BPC 157/NO system relations (for review, see, i.e., [39])

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However, if you are sensitive to methylated nutrients or already reacting to supplements, starting with single-ingredient B12 may be safer before introducing a full B-complex