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MANF reduces the expression of the pro-apoptotic factor CHOP by inhibiting the nuclear translocation of activating transcription factor 6 (ATF6), downregulating the generation of the XBP1s splice variant, and blocking activation of the PERK-eIF2 pathway [146]

Conclusions and Future Perspectives In addition to essential amino acids, many non-essential amino acids and semi-essential amino acids also need an extracellular supply
[DOI] [PMC free article] [PubMed] [Google Scholar] 325.Chih CP, Roberts EL Jr

Open 4, 980992

[Accessed on 24th June 2022] 5
