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Triaditis may cause decreased serum folate or cobalamin (B12) concentrations due to intestinal disease and/or pancreatitis
and others (Fig

As much as dietary antioxidants can alleviate acute stress, their chronic supplementation to healthy animals may interfere with normal ROS signaling, compromise homeostasis, and eventually accelerate, rather than decelerate, aging 4

These qualities make NAC especially beneficial for active people, the elderly and those exposed to polluted environments

The role of sirtuins in antioxidant and redox signaling
